MORISHIGE

List of Substances, Theraputics, Indications & Functions

 

B-Complex

All B vitamins help the body to convert carbohydrates into glucose, which is "burned" to produce energy.  These B vitamins are essential in the breakdown of fats and protein.  B-Complex vitamins also play an important role in maintaining the muscle tone in the gastrointestinal tract and promoting the health of the nervous system, skin, hair, eyes, moutn, and liver.  B-Complex vitamins are a popular choice of athletes. 

 

Some Benefits are:

• Improves Metabolism

• Maintains Normal Skin Function

• Improves Mood

• Reduces Water Retention

• Promotes a Normal Appetite

• Increases Red Blood Cell Production

• Improves Liver Function

• Boosts Production of Energy
   

Supplement B is responsible for offering cellular growth, cellular split, skin wellness, immunity process, stressed program, and also, in handling the actual metabolic methods. A deficiency of certain B vitamins can cause anemia, tiredness, loss of appetite, abdominal pain, depression, numbness and tingling in the arms and legs, muscle cramps, respiratory infections, hair loss, eczema, poor growth in children, and birth defects.

 

Most B-Complex injections may include the following vitamins:

• Vitamin B-1 (Thiamine): The water-soluble vitamin that all living organisms use in their biochemistry for the proper metabolism of starch and sugar and for effectively maintaining a healthy nervous system.

• Vitamin B-2 (Riboflavin 5-Phosphate): The easily absorbed micronutrient that is required for a wide variety of cellular processes and plays a key role in energy metabolism and helps the thyroid function properly.

• Vitamin B-3 (Niacinamide): The water-soluble vitamin that is essential for the normal function of the nervous system and the gastrointestinal tract; the severe lack of which is a potential contributing factor towards obesity.

• Vitamin B-5 (Calcium Pantothenate):  The essential vitamin to all forms of life that is a vital coenzyme in numerous chemical reactions that generate energy from food and promote cell reproduction and gene expression.

• Vitamin B-6 (Pyridoxine HCL):  The water-soluble vitamin that is a cofactor in many reactions of amino acid metabolism, including the synthesis of serotonin, and the maintenance of hormones and a stronger immune system.

• Vitamin B-12 (Cobalamin):  Plays a role in the body's growth and development. It also has a part in producing blood cells, nervous system function, and how the body uses folic acid and carbohydrates.

 

B-Complex injections should be given on a weekly basis (every 7-10 days) to maintain constant blood levels.

 

 

Cyanocobalamin/Methocobalamin (Vitamin B-12)

Vitamin B-12 is the "energy vitamin" as it often increases the energy level helping to prevent fatigue.  It also helps to suppress the appetite in weight loss programs as well as having a mild diuretic effect.  It stimulates the utilization of proteins, fats, and carbohydrates in the body. It is an essential water-soluble vitamin that is commonly found in a variety of foods such as fish, shellfish, meats, and dairy products. Vitamin B-12 is frequently used in combination with other B vitamins in a vitamin B complex formulation which is explained above.  It helps maintain healthy nerve cells and red blood cells and is also needed to make DNA, the genetic material in all cells.

 

Indications:

Pernicious (hemolytic) anemia 

Musculoskeletal - Back pain, Bursitis, Muscle cramps, Osteoporosis

Hemorrhage 

Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacteria overgrowth, total or partial gastrectomy, Constipation, Diarrhea, Fecal incontinence, Gastroparesis, Non-ulcer dyspepsia

Neurological- Alzheimer's disease, Anxiety, Dementia, Depression

Hepatic or renal disease 

Cardiovascular disease

Dermatological - Herpes zoster, Urticaria, Vitiligo, Neurodermatitis, Ichthyosis

ENT - Hearing loss, Olfactory dysfunction, Taste disorders, Tinnitus

Fish tapeworm infestation

Malignancy of pancreas or bowel

Folic acid deficiency

Vegan or Vegetarian Diets

 

Cyanocobalamin is rapidly absorbed from IM and SC injections delivering peak plasma levels within 1 hour after IM injection. B12 is transported via specific B12 binding proteins, transcobalamin I and II to the various tissues. The liver is main organ for storage of B12. 48 hrs post IM injection, 98% flushed in urine, verses the rapid excretion through IV administration which leaves little left for the liver. The majority of B12 is lost within 8 hrs after IM injection. 

 

Oral/Gastrointestinal absorption of B12 depends on the presence of sufficient intrinsic factor and calcium ions. Intrinsic factor deficiency causes pernicious anemia. The average US diet supplies 5 to 15 mcg/day of B12 in a protein-bound form which implies that B12 may not present in foods of plant origin, but is most abundant in foods of animal origin. Vegans and vegetarians are in high regards for B12 Injections.

 

 

Dexpanthenol (Vitamin B-5)

 

Pantothenic acid is a precursor of coenzyme A, a co-factor for a variety of enzyme-catalyzed reactions involving transfer of acetyl groups, responsible for the synthesis of certain steroids in adrenal glands and it’s a Acetylcholine neurotransmitter responsible for nerve impulses and detoxification in pathways. 

B-5 is part of ATP production in the Krebs cycle. It is important for fighting stress. During periods of stress, the body produces a hormone and neurotransmitter called adrenaline which requires the B-5 vitamin. Heart palpitations are a common symptom during stressful periods which may include but are not limited to strong emotions, vigorous activity, certain medicines, caffeine, alcohol, nicotine and some medical conditions. Insufficiency of vitamins B-6, B-9 and B-12 also can cause heart palpitations. B-5 nourishes the adrenal glands and can return excessive cortisol productions back to normal. When adrenals are stressed and fatigued B-5 can easily jump start them with proper dosing and a combination of specific minerals and supplements with counseling. 

B-5 is also involved in synthesis of fats including cholesterol and is essential for porphyrin – hemoglobin synthesis.

 

Other B-5 Clinical Indications: Acne Vulgaris, Allergic rhinitis, Hypoadrenalism, "Goose Stepping"...

 

 

 

Pyridoxine (Vitamin B-6)

 

Functions

Transamination – transfer of NH2 to another amino acid

Deamination – removes amino acid as energy source

Desulfuration – transfers sulfhydryl group from methionine to serine to form cysteine 

Decarboxylation – removes COOH from amino acid to form others 

Co-factor for >50 different enzymes

Neurotransmitters – serotonin, norepinephrine, histamine, 

P5P can be concentrated in brain – thought that dementia may be associated with decreased transport

Required for alpha aminolevulinic acid – in heme for hemoglobin

Tryptophan ->  niacin and breaksdown homocysteine 

Vital for formation of sphygolipids in development of myelin sheaths 

Helps crosslinking of callogen and elastin

Involved in synthesis of intrinsic factor 

 

Therapeutics

PMS

Neurological problems 

Neuropathy 

Depression 

Meniere's Disease, Vertigo, Taste Disorders

Dermatological issues 

Cardiovascular

Anemia 

Asthma 

 

 

Folic Acid

Folic acid, along with vitamin B12, is important for formation of red blood cells. Lack of these two vital nutrients leads to variety of anemia called macrocytic anemia. This means the red blood cells appear bloated and large and have a reduced capacity to carry oxygen.

Folate along with other B vitamins are also vital for nerve function. Folate is essential for the formation of DNA (genetic material) within every body cell. This allows normal replication of cells.

Biochemically folates act as chemicals that medicate one-carbon transfer reactions. These are important for formation of purines and pyrimidines. These purines and pyrimidines form basic building blocks for DNA.

Some evidence links a shortage of folate with depression.  Limited evidence from randomized controlled trials showed using folic acid in addition to antidepressants to be specific SSRIs, may have benefits. Research at the University of York and Hull York Medical School has found a link between depression and low levels of folate.

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Function: Synthesis of purines – guanine, adenine, and pyrimidine thymine; formation of mature RBC & WBC; folacin is carbon carrier in formation of heme; used to make glutamic acid; used to convert phenylalanine to tryosine. 

 

Therapeutics:

Neural tube defects

Cleft palate

Restless leg syndrome 

Cervical dysplasia

Depression 

Malabsorption & GI inflammation

Gingivitis or periodontal disease 

Gout 

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Hyaluronic Acid

Also known as Glycoaminoglycan, Hyluronic Acid acts as a network that transfers essential nutrients from the bloodstream to skin cells. High concentrations are found in soft connective tissues, fluid surrounding your eyes, cartilage and joint fluids, skin tissue, scalp tissue and hair follicles, lips and gum tissue. HA plays a key role in numerous areas of the body including the maintenance of skin volume and hydration, eye volume and shape and joint lubrication and cushioning.

 

When this gel is injected, it acts like an inflated cushion to support facial structures and tissues that may have lost volume or elasticity due to normal aging. For over a century now, various synthetic forms of hyaluronic acid have been developed and used to correct disorders in the fields of rheumatology, ophthalmology, and wound repair. Hyaluronic acid-based dermal fillers are the fastest growing non-invasive aesthetic procedure in the United States.

 

Hyaluronic Acid (HA) Theraputics: 

Pain Management 

Rheumatology 

Orthopedics 

Aesthetics

Wounds/burns/skin ulcers/moisturizer

 

As a joint injection HA protects against damage and friction between bones and cartilage, alternation of synovial fluid, and some tendon and ligament/connective tissues. Ha is found in the ECM of load-bearing joints. It is also a chief component of the interstitial gel. Hyaluronic acid is found on the inner surface of the cell membrane and is translocated out of the cell during biosynthesis. Hyaluronic acid acts as an environmental cue that regulates cell behavior during embryonic development, healing processes, inflammation, and tumor development. It interacts with a specific transmembrane receptor.

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Dextrose

 

Dextrose is a sclerosing agent that causes inflammation in the Intra Muscular and Subcutaneous tissues to promote healing.   

 

Dextrose Prolotherapy:

Pain 

Inflammation

Laxity of tissue 

Degenerated tissue

Neuralgia

Possibly Fibromyalgia

Joint & Cartilage Degradation 

 

*Contraindicated in patents with diabetes or sensitivity to corn products.